Case-02 : Health Economic Outcome Research (HEOR)

Introducing past case studies utilizing data from MDV Database.

Case Sample (Health Economics Outcome Research)

Retrospective Analysis of Medical Costs and Resource Utilization for Severe Hypoglycemic Events in Atients with Type 2 Diabetes in Japan

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Ikeda, Y., Kubo, T., Oda, E., Abe, M., & Tokita, S. (2019). Retrospective analysis of medical costs and resource utilization for severe hypoglycemic events in patients with type 2 diabetes in Japan. Journal of diabetes investigation, 10(3), 857–865. https://doi.org/10.1111/jdi.12959

Introduction

  • Within treatment of type 2 diabetes mellitus (T2DM) patients onset with hypoglycemia are seen and severe hypoglycemia events (SHE) requires hospital treatment.
  • Economic burden analysis has been conducted in Japan providing information on medical cost per SHE and overall medical cost for SHE but actual medical resource utilization after SHE is not confirmed.
  • This analysis is a follow-up analysis based on the prior retrospective study confirming the incidence rate and factors associates with severe hypoglycemia in patients with T2DM patients.

Objective of Study

To underline the actual medical costs and hospitals stay or visits due to SHEs in Japan

Study Design and Criteria

Study Design: Retrospective Observational Study

Target Period: April 2008 – September 2014

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Definition of Severe Hypoglycemic Episodes

Severe Hypoglycemic Episode broken down into the following categories.

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Patient Characteristics of the Study Population

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Flow Chart Showing Patient Composition for Cost Analysis

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Medical Costs Per Severe Hypoglycemic Event

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Composition of the Medical Costs

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Conclusion

  • Direct costs of SHEs were high in Japan
  • Most medical resources were required for the following.
  • 1.Diagnosis and testing
  • 2.Treatment of related symptoms and after-effects
  • 3.Treatment for SHEs
  • T2DM patients are prone to hypoglycemia as the patient ages
  • To implement more ersonal management under guidelines in order to reduce hypoglycemia

⇒Ultimately decreases the economic burden of diabetic patients

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