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Changes in the number of patients with syphilis from the 1st quarter of 2019 to the 4th quarter of 2022 , and distribution of the patients by sex and age 

In the tables below, the National Institute of Infectious Diseases reported a constant and rapid increase in the number of syphilis patients between 1Q 2019 and 4Q 2022  

Changes in the number of syphilis reports from 2019 1Q to 2022 4Q

Changes in the number of syphilis reports from 2019 1Q to 2022 4Q

The graph is created by our company based on the latest “Notable Infectious Diseases ” /IDWR bulletin data from the NIID National Institute of Infectious Diseases .
https://www.niid.go.jp/niid/ja/idwr.html _
https://www.niid.go.jp/niid/ja/data/12183-idwr-sokuho-data-j-2331.html _

Number of reports of syphilis by age group ( 2022 ) *

*For 2022, the report covers the aggregate values as of November 9 , 2022 for the 1st to 44th weeks .

Ministry of Health, Labor and Welfare HP : Quoted from “ Health and Medical Care: Syphilis ” page https://www.mhlw.go.jp/stf/seisakunitsuite/bunya/kenkou_iryou/kenkou/kekkaku-kansenshou/seikansenshou/syphilis.html

Next, regarding syphilis, we looked at the number of patients with syphilis from the 1st quarter of 2019 to the 4th quarter of 2022 and the distribution by sex and age in 2022 from the MDV data .
First, we tabulated only the disease condition.

* Aggregation of 22,005,800 actual patients at 378 facilities with complete data from January 2019 to December 2022

Syphilis patient extraction definition
Disease code/ ICD10 code: A50・A51・A52・A53

Figure 1-1 : Changes in the number of syphilis patients from 1Q 2019 to 4Q 2022 ( disease conditions only )

Figure 2-1 : Distribution of syphilis patients by sex and age in 2022 ( disease conditions only )

Since there was a large difference in the distribution by sex and age, considering the possibility of past history and false positives in the diagnosis of syphilis, Tests and drugs for syphilis were added to the conditions, and the transition in the number of patients from the 1st Q of 2019 to the 4th Q of 2022 and the distribution by sex and age in 2022 were recalculated.

* 1: Refer to the Japanese Society for Sexually Transmitted Infectious Diseases, Syphilis Treatment Guide 2nd Edition

Syphilis patient extraction definition
Disease code/ ICD10 code: A50・A51・A52・A53
Drug code / generic name (amoxicillin hydrate, benzylpenicillin benzathine hydrate )
Clinical code /Treponemal syphilis antibody and RPR ( STS )

Figure 1-2 : Changes in the number of syphilis patients from 1Q 2019 to 4Q 2022 (disease, examination, and drug

Figure 2-2 : Distribution of syphilis patients by gender and age group in 2022 ( disease, examination, and drug conditions)

Although the number of patients continues to increase, Figure 2-2 shows that the majority of patients are men in their 20’s to 50’s and female patients in their 20’s in a similar trend as reported by the Ministry of Health, Labor & Welfare

Note: This article was published on September 1, 2023.

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