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Latest Rankings by Database

We update our monthly rankings using the most recent year of data extracted from each database. These rankings offer insight into the scale of our DPC and insurer databases—the largest of their kind in Japan.

These rankings are aggregated using MDV analyzer, based on MDV’s medical databases. The DPC data covers approximately 35% of acute care (DPC) hospitals in Japan* and is notable for its extensive information on elderly patients. The health insurance data features traceability across medical facilities,covering data from both the National Health Insurance and the Medical Care System For The Elderly. *As of March 1, 2026.

MDV Database Overview

ランクアイコンPrescription Drugs by Sales Amount

DPC Data (March 2025-February 2026)
Product Name Actual Number of Patients Total Cost (JPY)
1 Keytruda 25,352 70,565,216,035
2 Opdivo 14,769 40,651,526,398
3 Tagrisso 10,919 36,558,379,762
4 Imfinzi 8,497 33,519,899,154
5 Ultomiris 825 27,843,227,185
6 Tecentriq 7,387 24,912,591,277
7 Darzquro 5,408 23,363,844,305
8 Verzenio 10,232 22,836,630,562
9 Xtandi 15,306 22,471,006,958
10 Ofev 10,480 20,434,362,441
Health Insurance Data (February 2025-January 2026)
Product Name Actual Number of Patients Total Cost (JPY)
1 Dupixent 8,682 6,420,138,921
2 Ultomiris 119 3,868,172,085
3 Keytruda 1,309 3,576,110,656
4 Hemlibra 130 3,254,723,665
5 Verzenio 1,178 2,929,957,176
6 Mounjaro 17,020 2,271,949,070
7 Rinvoq 1,927 2,162,933,435
8 Humira 1,818 2,000,831,511
9 Stelara 1,053 1,796,203,297
10 Rybelsus 23,533 1,740,089,249

ランクアイコンPrescription Drugs by Sales Amount Among Dermatological Drugs

DPC Data (March 2025-February 2026)
Product Name Actual Number of Patients Total Cost (JPY)
1 Keytruda 11,359 14,692,109,832
2 Platelet Concentrate (NISSEKI) 20,855 10,233,220,207
3 Tagrisso 5,833 10,103,285,960
4 Opdivo 6,245 8,653,242,777
5 Vectibix 4,922 7,502,411,187
6 Dupixent 11,933 7,173,341,316
7 Red Blood Cells (NISSEKI) 97,913 6,390,782,929
8 Imfinzi 3,054 5,295,648,870
9 Skyrizi 3,187 4,644,205,374
10 Tecentriq 2,827 4,228,243,259
Health Insurance Data (February 2025-January 2026)
Product Name Actual Number of Patients Total Cost (JPY)
1 Dupixent 6,766 3,793,442,911
2 Moizerto 78,034 1,475,814,980
3 Hirudoid 255,301 1,051,345,650
4 Keytruda 669 779,914,728
5 Platelet Concentrate (NISSEKI) 1,221 769,760,427
6 Rinvoq 963 736,151,872
7 Corectim 86,252 676,246,664
8 Skyrizi 520 667,133,759
9 Bepio 119,690 642,210,303
10 Tagrisso 274 543,961,555

Note: The above ranking is extracted from health insurance data. Data from the National Health Insurance and Medical Care System for the Elderly are not included.

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