55.45

Million
Patients

Hospital Database

(Last updated: January 2026)
[Data availability: April 2008 to end of November 2025]
The start date of available data varies by hospital.
Hospital data is a compilation of receipt and DPC data allocated to a single patient ID registered in the medical institution, allowing longitudinal tracking of treatments and disease progression within that hospital.

21.02

Million
Patients

Health Insurance
Database

(Last updated: December 2023)
[Data availability: April 2012 to end of September 2023]

Database Insights &
Rankings

We analyze Japan’s largest hospital database to deliver regularly updated rankings and key trends each month.

①-1 Top 10 Prescription Drugs by Sales Amount in DPC Data (December 2024-November 2025)
Product Name Actual Number of Patients Total Cost (JPY)
1 Keytruda 20,599 57,289,938,348
2 Opdivo 12,510 34,689,609,790
3 Tagrisso 8,781 29,732,381,750
4 Imfinzi 6,797 27,016,477,783
5 Ultomiris 653 21,993,780,130
①-2 Top 10 Prescription Drugs by Sales Amount in Health Insurance Data (November 2024-October 2025)
Product Name Actual Number of Patients Total Cost (JPY)
1 Dupixent 8,466 6,392,449,833
2 Ultomiris 118 4,091,247,015
3 Keytruda 1,286 3,564,313,266
4 Hemlibra 132 3,425,827,435
5 Verzenio 1,181 2,913,437,555
②-1 Top 10 Prescription Drugs by Sales Amount Among Dermatological Drugs in DPC Data (December 2024-November 2025)
Product Name Actual Number of Patients Total Cost (JPY)
1 Keytruda 9,146 11,809,616,386
2 Platelet Concentrate (NISSEKI) 17,031 8,170,409,124
3 Tagrisso 4,672 8,157,622,603
4 Opdivo 5,284 7,308,018,319
5 Vectibix 3,978 6,148,523,426
②-2 Top 10 Prescription Drugs by Sales Amount Among Dermatological Drugs in Health Insurance Data (November 2024-October 2025)
Product Name Actual Number of Patients Total Cost (JPY)
1 Dupixent 6,646 3,917,596,605
2 Moizerto 76,833 1,411,695,467
3 Hirudoid 271,048 1,112,355,609
4 Platelet Concentrate (NISSEKI) 1,261 792,687,756
5 Keytruda 652 776,911,756

FAQ

Answers to frequently asked questions about MDV’s real-world clinical data.

No. Our databases includes both inpatient and outpatient insurance claims data.
As of January 1, 2026, our coverage includes 605 of the 1,786 DPC-designated hospitals in Japan.
DPC stands for Diagnosis Procedure Combination. Unlike the traditional fee for service reimbursement model, the DPC system is a flat sum reimbursement scheme for inpatient care. Medical fees are calculated using fixed daily rates determined by the MHLW (Ministry of Health, Labour and Welfare), based on the patient’s diagnosis, disease severity, presence of surgery or complications, and details of the treatments provided.
Hospitals designated under the DPC system are also required to submit DPC data to the MHLW on a quarterly basis.
Yes. Through our Health Insurance Database, data from clinic visits are also available. Beside providing insurance claim data from DPC hospitals, MDV is also supplying data from the Health Insurance Societies and National Health Insurance thanks to partnership with external providers.
Each DPC hospital assigns a unique ID to each patient, so it is possible to track both inpatient and outpatient visits within the same DPC hospital, but it is not possible to track patients after they have been transferred to another hospital.

CONTACT US

For any questions about our EBM services or clinical databases, please feel free to get in touch.

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