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Latest Rankings by Database

We update our monthly rankings using the most recent year of data extracted from each database.
These rankings offer insight into the scale of our DPC and insurer databases—the largest of their kind in Japan.

These rankings are aggregated using MDV analyzer, based on MDV’s medical databases. The DPC data covers approximately 28% of acute care (DPC) hospitals in Japan* and is notable for its extensive information on elderly patients.
The health insurance data features traceability across medical facilities,covering data from both the National Health Insurance and the Medical Care System For The Elderly.
*As of December 1, 2023.

ランクアイコン Prescription Drugs by Sales Amount

DPC Data (December 2024-November 2025)
Product Name Actual Number of Patients Total Cost (JPY)
1 Keytruda 20,599 57,289,938,348
2 Opdivo 12,510 34,689,609,790
3 Tagrisso 8,781 29,732,381,750
4 Imfinzi 6,797 27,016,477,783
5 Ultomiris 653 21,993,780,130
6 Tecentriq 6,094 20,408,794,472
7 Darzquro 4,190 18,543,134,479
8 Verzenio 8,149 18,344,985,766
9 Xtandi 12,015 17,771,417,845
10 Platelet Concentrate (NISSEKI) 31,107 16,014,991,341
Health Insurance Data (December 2024-November 2025)
Product Name Actual Number of Patients Total Cost (JPY)
1 Dupixent 8,466 6,392,449,833
2 Ultomiris 118 4,091,247,015
3 Keytruda 1,286 3,564,313,266
4 Hemlibra 132 3,425,827,435
5 Verzenio 1,181 2,913,437,555
6 Rinvoq 1,894 2,162,714,951
7 Humira 1,898 2,113,547,970
8 Mounjaro 15,058 1,933,035,893
9 Stelara 1,078 1,877,105,900
10 Rybelsus 23,351 1,735,039,359

ランクアイコンPrescription Drugs by Sales Amount Among Dermatological Drugs

DPC Data (November 2024-October 2025)
Product Name Actual Number of Patients Total Cost (JPY)
1 Keytruda 9,146 11,809,616,386
2 Platelet Concentrate (NISSEKI) 17,031 8,170,409,124
3 Tagrisso 4,672 8,157,622,603
4 Opdivo 5,284 7,308,018,319
5 Vectibix 3,978 6,148,523,426
6 Dupixent 9,218 5,468,589,160
7 Red Blood Cells (NISSEKI) 78,376 5,216,392,302
8 Imfinzi 2,471 4,278,204,904
9 Skyrizi 2,525 3,730,562,272
10 Tecentriq 2,344 3,524,196,088
Health Insurance Data (November 2024-October 2025)
Product Name Actual Number of Patients Total Cost (JPY)
1 Dupixent 6,646 3,917,596,605
2 Moizerto 76,833 1,411,695,467
3 Hirudoid 271,048 1,112,355,609
4 Platelet Concentrate (NISSEKI) 1,261 792,687,756
5 Keytruda 652 776,911,756
6 Rinvoq 952 743,936,660
7 Corectim 88,196 693,528,980
8 Skyrizi 511 654,541,997
9 Bepio 116,323 609,309,068
10 Tagrisso 271 555,067,135

Note: The above ranking is extracted from health insurance data. Data from the National Health Insurance and Medical Care System for the Elderly are not included.

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